Thursday, 16 January 2014

Top 10 weird diseases around the world

One of the causes for the thinning world population is through disease. Have a look at some of the weird diseases in the world. Some diseases have no cure in this list which are deadly.

1. Progeria:

          Progeria is an extremely rare genetic disease of childhood characterized by dramatic, premature aging. When the disease reaches its peak it is known as Progeria (Hutchinson-Gilford progeria syndrome, HGPS, Progeria syndrome).
          Children affected by Progeria Syndrome will look normal at birth. After a year they shed all their hair including eyebrows, they weigh less, their growth stops. Progeria makes the child look older with small face, baldness and aged- looking skin.  Death occurs on average at age 13, usually from heart attack or stroke.


          Neurofibromatosis is a genetic disorder of the nervous system. It mainly affects how nerve cells form and grow. It causes tumors to grow on nerves. You can get neurofibromatosis from your parents, or it can happen because of a mutation (change) in your genes. Once you have it, you can pass it along to your children. Usually the tumors are benign, but sometimes they can become cancerous.
          Three types of Neurofibromatosis:

  • type -I: Nerve tissue grows tumors which causes changes in skin.
  • type -II: hearing loss and poor balance.
  • Schwannomatosis: Causes intense pain.

3. Fibrodysplasia ossificans progressiva (FOP):

 Fibrodysplasia ossificans progressiva is an disorder in which the muscle tissue like ligaments gets replaced by bones. The bones grow up anywhere in their body replacing all the muscle tissues. Sufferers are slowly imprisoned by their own skeleton.

4. Epidermodysplasia verruciformis:

          Epidermodysplasia verruciformis is an extremely rare hereditary skin disorder.  It is characterized by abnormal susceptibility to  human papillomaviruses (HPVs) of the skin. It grows scaly macules and papules, particularly on the hands and feet.

5. Hypertrichosis:

          Hypertrichosis is genrally known as Werewolf Syndrome is an abnormal amount of hair growth over the body. This syndrome is categorized into Generalized Hypertrichosis, hair growth over the entire body and Localized Hypertrichosis, hair growth in a certain area.

6. Porphyria:

         Porphyria is a group of disorders caused by abnormalities in the chemical steps that lead to heme production. Heme is a vital molecule for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. Symptomatically, acute porphyrias primarily present with nervous system involvement, often with severe abdominal pain, vomiting, neuropathy and mental disturbances. Cutaneous porphyrias present with skin manifestations often after exposure to sun due to the accumulation of excess porphyrins near the surface of the skin.

7. Kuru:

            Kuru is an incurable degenerative neurological disorder endemic to tribal regions of Papua New Guinea. The disease was the result of the practice of ritualistic cannibalism among the Fore, in which relatives prepared and consumed the tissues (including brain) of deceased family members. People affected by this disease will suffer with decreased muscle control in the initial stage. In the final stage they are unable to speak, unable to stand and has dysphagia. An infected person usually dies within 3 months to 2 years after the first symptoms, often because of pneumonia or pressure sores infection.

8. Tetanus:

            Tetanus is a serious illness caused by Clostridium bacteria.The infection causes painful tightening of the muscles, usually all over the body. It can lead to "locking" of the jaw. This makes it impossible to open your mouth or swallow.

9. Alice in Wonderland Syndrome:

          Alice in Wonderland Syndrome (AIWS) is a set of symptoms including the alteration of body image and the alteration of visual perception. It makes the sufferer feel as though parts of their body are changing size and as though the sizes of objects are changing.

10. Dermatographia:

          Dermatographia is an skin disorder. Even rubbing, scratching or even a slap will make the skin inflammed and raised. The skin will be extremely sensitive with weak membrane which can be easily and rapidly breaks down under physical pressure causing an allergic- like reaction.

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